A boron based antifungal agent in complex with its target protein domain
نویسندگان
چکیده
منابع مشابه
A Time-Domain Method for Shape Reconstruction of a Target with Known Electrical Properties (RESEARCH NOTE)
This paper uses a method for shape reconstruction of a 2-D homogeneous object with arbitrary geometry and known electrical properties. In this method, the object is illuminated by a Gaussian pulse, modulated with sinusoidal carrier plane wave and the time domains’ footprint signal due to object presence is used for the shape reconstruction. A nonlinear feedback loop is used to minimize the diff...
متن کاملIn-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need...
متن کاملIn-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
Mycobacterium tuberculosis, the main cause of tuberculosis (TB), has still remained a global health crisis especially in developing countries. Tuberculosis treatment is a laborious and lengthy process with high risk of non compliance, cytotoxicity adverse events and drug resistance in patient. Recently, there has been an alarming rise of drug resistant in TB. In this regard, it is an unmet need...
متن کاملHaloprogin: a topical antifungal agent.
Haloprogin was shown to be a highly effective agent for the treatment of experimentally induced topical mycotic infections in guinea pigs. Its in vitro spectrum of activity also includes yeasts, yeastlike fungi (Candida species), and certain gram-positive bacteria. The in vitro and in vivo antifungal activity of haloprogin against dermatophytes was equal to that observed with tolnaftate. The st...
متن کاملProtein complex prediction based on maximum matching with domain-domain interaction.
With the development of high-throughput methods for identifying protein-protein interactions, large scale interaction networks are available. Computational methods to analyze the networks to detect functional modules as protein complexes are becoming more important. However, most of the existing methods only make use of the protein-protein interaction networks without considering the structural...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2007
ISSN: 0108-7673
DOI: 10.1107/s0108767307093488